BDBM50020077 CHEMBL3288152

SMILES: OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc2n(ccc2c1)C(=O)Nc1ccccc1

InChI Key: InChIKey=YSQVVCXSUZWLNZ-DNQXCXABSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020077 (CHEMBL3288152) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc2n(ccc2c1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C28H24N2O4/c31-26(23-7-4-8-24(23)27(32)33)19-11-9-18(10-12-19)20-13-14-25-21(17-20)15-16-30(25)28(34)29-22-5-2-1-3-6-22/h1-3,5-6,9-17,23-24H,4,7-8H2,(H,29,34)(H,32,33)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
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