BDBM50020156 2-Benzyl-N-(1-benzyl-2-hydroxycarbamoyl-ethyl)-malonamic acid(RR+RS)::CHEMBL57623

SMILES: ONC(=O)CC(Cc1ccccc1)NC(=O)C(Cc1ccccc1)C(O)=O

InChI Key: InChIKey=LOZHIAIAXILPEC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50020156 (2-Benzyl-N-(1-benzyl-2-hydroxycarbamoyl-ethyl)-mal...) Show SMILES ONC(=O)CC(Cc1ccccc1)NC(=O)C(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H22N2O5/c23-18(22-27)13-16(11-14-7-3-1-4-8-14)21-19(24)17(20(25)26)12-15-9-5-2-6-10-15/h1-10,16-17,27H,11-13H2,(H,21,24)(H,22,23)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
UA 498 CNRS Curated by ChEMBL					Assay Description Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)				J Med Chem 31: 1825-31 (1988) BindingDB Entry DOI: 10.7270/Q2R49RC8
					More data for this Ligand-Target Pair