BDBM50020180 4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL541077::CHEMBL58613
SMILES: Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cccc2ccoc12
InChI Key: InChIKey=HUACSDTUNPSEBC-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50020180 (4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena... | J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50020180 (4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-p...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duphar Research Laboratories Curated by ChEMBL | Assay Description Potency to displace [3H]- WB-4101 from alpha-1 adrenergic receptor in rat striatum | J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50020180 (4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duphar Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatum | J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50020180 (4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duphar Research Laboratories Curated by ChEMBL | Assay Description Potency to displace [3H]- Spiperone from 5-hydroxytryptamine 2 receptor in rat striatum | J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB | |||||||||||
More data for this Ligand-Target Pair |