BDBM50020272 (RS)-1-(4-Chloro-phenyl)-3-[5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea::CHEMBL289533

SMILES: Fc1ccccc1C1=NC(NC(=O)Nc2ccc(Cl)cc2)C(=O)Nc2ccccc12

InChI Key: InChIKey=REOVDJIBQLUDPV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50020272 ((RS)-1-(4-Chloro-phenyl)-3-[5-(2-fluoro-phenyl)-2-...) Show SMILES Fc1ccccc1C1=NC(NC(=O)Nc2ccc(Cl)cc2)C(=O)Nc2ccccc12 |t:8| Show InChI InChI=1S/C22H16ClFN4O2/c23-13-9-11-14(12-10-13)25-22(30)28-20-21(29)26-18-8-4-2-6-16(18)19(27-20)15-5-1-3-7-17(15)24/h1-12,20H,(H,26,29)(H2,25,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreas				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020272 ((RS)-1-(4-Chloro-phenyl)-3-[5-(2-fluoro-phenyl)-2-...) Show SMILES Fc1ccccc1C1=NC(NC(=O)Nc2ccc(Cl)cc2)C(=O)Nc2ccccc12 |t:8| Show InChI InChI=1S/C22H16ClFN4O2/c23-13-9-11-14(12-10-13)25-22(30)28-20-21(29)26-18-8-4-2-6-16(18)19(27-20)15-5-1-3-7-17(15)24/h1-12,20H,(H,26,29)(H2,25,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortex				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020272 ((RS)-1-(4-Chloro-phenyl)-3-[5-(2-fluoro-phenyl)-2-...) Show SMILES Fc1ccccc1C1=NC(NC(=O)Nc2ccc(Cl)cc2)C(=O)Nc2ccccc12 |t:8| Show InChI InChI=1S/C22H16ClFN4O2/c23-13-9-11-14(12-10-13)25-22(30)28-20-21(29)26-18-8-4-2-6-16(18)19(27-20)15-5-1-3-7-17(15)24/h1-12,20H,(H,26,29)(H2,25,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glands				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair