BDBM50020410 CHEMBL3289812

SMILES: Nc1nc2ccc(OC3CNC3)nc2n1CC(O)c1ccc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=VUWBGLZAEMROMC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50020410 (CHEMBL3289812) Show SMILES Nc1nc2ccc(OC3CNC3)nc2n1CC(O)c1ccc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C18H17ClF3N5O2/c19-12-5-9(18(20,21)22)1-2-11(12)14(28)8-27-16-13(25-17(27)23)3-4-15(26-16)29-10-6-24-7-10/h1-5,10,14,24,28H,6-8H2,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 57: 5702-13 (2014) Article DOI: 10.1021/jm500535j BindingDB Entry DOI: 10.7270/Q2X3501C
					More data for this Ligand-Target Pair