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SMILES: COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cc(CNC(=O)OC(C)(C)C)cs1

InChI Key: InChIKey=XIGJGOGOOCFYJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020454   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin alpha-1A chain


(Sus scrofa (Pig))		BDBM50020454
PNG
(CHEMBL133877 | {5-[4-(tert-Butoxycarbonylamino-met...)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cc(CNC(=O)OC(C)(C)C)cs1
Show InChI InChI=1S/C20H22N4O5S/c1-20(2,3)29-18(26)21-9-11-7-15(30-10-11)16(25)12-5-6-13-14(8-12)23-17(22-13)24-19(27)28-4/h5-8,10H,9H2,1-4H3,(H,21,26)(H2,22,23,24,27)
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.33E+4n/an/an/an/an/an/a



Smith Kline & French Laboratories

Curated by ChEMBL


Assay Description
Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.

J Med Chem 32: 409-17 (1989)


BindingDB Entry DOI: 10.7270/Q2125RN4
More data for this
Ligand-Target Pair