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SMILES: COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cc(cs1)C(=O)C(F)(F)F

InChI Key: InChIKey=RZXMCOSXLCPHLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin alpha-1A chain


(Sus scrofa (Pig))		BDBM50020469
PNG
(CHEMBL134616 | {5-[4-(2,2,2-Trifluoro-acetyl)-thio...)
Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cc(cs1)C(=O)C(F)(F)F
Show InChI InChI=1S/C16H10F3N3O4S/c1-26-15(25)22-14-20-9-3-2-7(4-10(9)21-14)12(23)11-5-8(6-27-11)13(24)16(17,18)19/h2-6H,1H3,(H2,20,21,22,25)
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Smith Kline & French Laboratories

Curated by ChEMBL


Assay Description
Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.

J Med Chem 32: 409-17 (1989)


BindingDB Entry DOI: 10.7270/Q2125RN4
More data for this
Ligand-Target Pair