null

SMILES: Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I

InChI Key: InChIKey=SRQUFBCRUHYBHN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) Show SMILES Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I Show InChI InChI=1S/C19H21F3IN3/c20-19(21,22)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-18(24)17(23)12-14/h1-5,12-13H,6-11,24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus				J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) Show SMILES Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I Show InChI InChI=1S/C19H21F3IN3/c20-19(21,22)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-18(24)17(23)12-14/h1-5,12-13H,6-11,24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampus				J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) Show SMILES Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I Show InChI InChI=1S/C19H21F3IN3/c20-19(21,22)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-18(24)17(23)12-14/h1-5,12-13H,6-11,24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus				J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) Show SMILES Nc1ccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1I Show InChI InChI=1S/C19H21F3IN3/c20-19(21,22)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-18(24)17(23)12-14/h1-5,12-13H,6-11,24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampus				J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3
					More data for this Ligand-Target Pair