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BDBM50021099 CHEMBL3287641

SMILES: Fc1ccc(cc1)C(=O)NC1CCC(CC1)NCc1c[nH]c2ccccc12

InChI Key: InChIKey=KUHPLHLNZSKDDK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021099   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50021099
PNG
(CHEMBL3287641)
Show SMILES Fc1ccc(cc1)C(=O)NC1CCC(CC1)NCc1c[nH]c2ccccc12 |(44.94,-14.71,;43.61,-15.49,;43.61,-17.04,;42.27,-17.81,;40.94,-17.04,;40.94,-15.49,;42.27,-14.72,;39.6,-17.81,;38.27,-17.03,;39.6,-19.35,;38.27,-20.12,;36.94,-19.34,;35.61,-20.1,;35.59,-21.64,;36.93,-22.42,;38.27,-21.65,;34.26,-22.41,;34.26,-23.95,;32.93,-24.72,;31.52,-24.1,;30.49,-25.25,;31.27,-26.57,;30.79,-28.03,;31.82,-29.17,;33.33,-28.85,;33.8,-27.39,;32.77,-26.26,)|
Show InChI InChI=1S/C22H24FN3O/c23-17-7-5-15(6-8-17)22(27)26-19-11-9-18(10-12-19)24-13-16-14-25-21-4-2-1-3-20(16)21/h1-8,14,18-19,24-25H,9-13H2,(H,26,27)
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Similars
Article
PubMed
>1.20E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]SS14 from human SST3 expressed in CHO membrane after 60 to 90 mins by scintillation counting

ACS Med Chem Lett 5: 690-5 (2014)


Article DOI: 10.1021/ml500079u
BindingDB Entry DOI: 10.7270/Q22N53V4
More data for this
Ligand-Target Pair