BDBM50021189 5-Aminomethyl-4,5-dihydro-isoxazol-3-ol::CHEMBL40804

SMILES: NC[C@H]1CC(O)=NO1

InChI Key: InChIKey=ZHCZZTNIHDWRNS-GSVOUGTGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA transporter (Rattus norvegicus)	BDBM50021189 (5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL40...) Show SMILES NC[C@H]1CC(O)=NO1 |c:5| Show InChI InChI=1S/C4H8N2O2/c5-2-3-1-4(7)6-8-3/h3H,1-2,5H2,(H,6,7)/t3-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibition of GABA uptake in rat brain synaptic membranes				J Med Chem 28: 1612-7 (1985) BindingDB Entry DOI: 10.7270/Q2PN94NZ
					More data for this Ligand-Target Pair
GABA receptor gamma-1 subunit (Rattus norvegicus)	BDBM50021189 (5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL40...) Show SMILES NC[C@H]1CC(O)=NO1 |c:5| Show InChI InChI=1S/C4H8N2O2/c5-2-3-1-4(7)6-8-3/h3H,1-2,5H2,(H,6,7)/t3-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranes				J Med Chem 28: 1612-7 (1985) BindingDB Entry DOI: 10.7270/Q2PN94NZ
					More data for this Ligand-Target Pair