BDBM50021355 CHEMBL3287946
SMILES: CC(C)CCNC(=O)CCn1cc(Br)c2ncccc2c1=O
InChI Key: InChIKey=KBCCCMSXXWIVPH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
20S proteasome chymotrypsin-like (Homo sapiens (Human)) | BDBM50021355 (CHEMBL3287946) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Messina Curated by ChEMBL | Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay | Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC | |||||||||||
More data for this Ligand-Target Pair |