BDBM50021516 2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::CHEMBL291332

SMILES: COc1cc(cc(OC)c1OC)C1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=YCCPYTPBHUIHGW-AAFJCEBUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50021516 (2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...) Show SMILES COc1cc(cc(OC)c1OC)C1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet activating factor receptor (Cavia porcellus)	BDBM50021516 (2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...) Show SMILES COc1cc(cc(OC)c1OC)C1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16?/m1/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PAF receptor binding to rabbit platelet plasma membranes				J Med Chem 29: 1917-21 (1986) BindingDB Entry DOI: 10.7270/Q2X63KZS
					More data for this Ligand-Target Pair