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BDBM50021531 CHEMBL3290577

SMILES: CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(F)cc1

InChI Key: InChIKey=PYNCNYHPZNOBJC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021531   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50021531
PNG
(CHEMBL3290577)
Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C14H17FN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
378n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...


Eur J Med Chem 83: 534-46 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.032
BindingDB Entry DOI: 10.7270/Q2W097HQ
More data for this
Ligand-Target Pair