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SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5C(F)(F)F)c(=O)cc4C)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=FRFNHPYRKFRMMZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021575   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50021575
PNG
(CHEMBL3290910)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5C(F)(F)F)c(=O)cc4C)cc3F)ccnc2cc1OCCCN1CCCC1
Show InChI InChI=1S/C36H33F4N5O5/c1-22-18-33(46)45(28-9-4-3-8-25(28)36(38,39)40)43-34(22)35(47)42-23-10-11-30(26(37)19-23)50-29-12-13-41-27-21-32(31(48-2)20-24(27)29)49-17-7-16-44-14-5-6-15-44/h3-4,8-13,18-21H,5-7,14-17H2,1-2H3,(H,42,47)
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Similars
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate by homogeneous time-resolved fluorescence assay

Eur J Med Chem 83: 581-93 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.068
BindingDB Entry DOI: 10.7270/Q2R78GTF
More data for this
Ligand-Target Pair