BDBM50021964 CHEMBL284828::Sodium; 3-methyl-2,2,6-trioxo-3-(4-trimethylsilanyl-[1,2,3]triazol-1-ylmethyl)-2lambda*6*-thia-bicyclo[3.2.0]heptane-4-carboxylate

SMILES: C[C@]1(Cn2cc(nn2)[Si](C)(C)C)[C@@H](C2C(CC2=O)S1(=O)=O)C([O-])=O

InChI Key: InChIKey=NNBVKIUYCIQKNA-UOTDJEAJSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (TEM-1) (Escherichia coli)	BDBM50021964 (CHEMBL284828 | Sodium; 3-methyl-2,2,6-trioxo-3-(4-...) Show SMILES C[C@]1(Cn2cc(nn2)[Si](C)(C)C)[C@@H](C2C(CC2=O)S1(=O)=O)C([O-])=O Show InChI InChI=1S/C14H21N3O5SSi/c1-14(7-17-6-10(15-16-17)24(2,3)4)12(13(19)20)11-8(18)5-9(11)23(14,21)22/h6,9,11-12H,5,7H2,1-4H3,(H,19,20)/p-1/t9?,11?,12-,14-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against Beta-lactamase from Bacillus sp. using penicillin G as substrate				J Med Chem 30: 1469-74 (1987) BindingDB Entry DOI: 10.7270/Q28G8JQ0
					More data for this Ligand-Target Pair