BDBM50022108 CHEMBL3298228
SMILES: COc1cccc2nc(O)nc(NCC(C)(C)c3ccccc3)c12
InChI Key: InChIKey=WAYXJKGOWYBZSE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human)) | BDBM50022108 (CHEMBL3298228) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current | Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP | |||||||||||
More data for this Ligand-Target Pair |