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BDBM50022150 CHEMBL158113::N*4*-Benzyl-6-chloro-pyrimidine-2,4-diamine

SMILES: Nc1nc(Cl)cc(NCc2ccccc2)n1

InChI Key: InChIKey=GXNJAZPAQIPYMJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022150   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase III


(Bacillus subtilis)		BDBM50022150
PNG
(CHEMBL158113 | N*4*-Benzyl-6-chloro-pyrimidine-2,4...)
Show SMILES Nc1nc(Cl)cc(NCc2ccccc2)n1
Show InChI InChI=1S/C11H11ClN4/c12-9-6-10(16-11(13)15-9)14-7-8-4-2-1-3-5-8/h1-6H,7H2,(H3,13,14,15,16)
KEGG

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CHEMBL
PC cid
PC sid
UniChem

Patents
PubMed
 1.70E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory activity against Bacillus subtilis DNA topoisomerase III using DNA Polymerase assay

J Med Chem 29: 676-81 (1986)


BindingDB Entry DOI: 10.7270/Q2MP528D
More data for this
Ligand-Target Pair