BDBM50022212 CHEMBL33167::N-Methyl-N-[3-(quinolin-2-ylmethoxy)-phenyl]-succinamic acid methyl ester

SMILES: COC(=O)CCC(=O)N(C)c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=YLZZTAFNQLJAPD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50022212 (CHEMBL33167 | N-Methyl-N-[3-(quinolin-2-ylmethoxy)...) Show SMILES COC(=O)CCC(=O)N(C)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H22N2O4/c1-24(21(25)12-13-22(26)27-2)18-7-5-8-19(14-18)28-15-17-11-10-16-6-3-4-9-20(16)23-17/h3-11,14H,12-13,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair