BDBM50022310 CHEMBL3298244

SMILES: FC(F)(F)Oc1ccccc1-c1ccc2[nH]ncc2c1

InChI Key: InChIKey=OARAWCIGFKPUOQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50022310 (CHEMBL3298244) Show SMILES FC(F)(F)Oc1ccccc1-c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C14H9F3N2O/c15-14(16,17)20-13-4-2-1-3-11(13)9-5-6-12-10(7-9)8-18-19-12/h1-8H,(H,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior ...				J Med Chem 57: 5129-40 (2014) Article DOI: 10.1021/jm401986p BindingDB Entry DOI: 10.7270/Q2833TKT
					More data for this Ligand-Target Pair