BDBM50022316 CHEMBL3298250

SMILES: Fc1c(ccc2[nH]ncc12)-c1ccccc1C(F)(F)F

InChI Key: InChIKey=XTEOOQGHFDZVDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50022316 (CHEMBL3298250) Show SMILES Fc1c(ccc2[nH]ncc12)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C14H8F4N2/c15-13-9(5-6-12-10(13)7-19-20-12)8-3-1-2-4-11(8)14(16,17)18/h1-7H,(H,19,20)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior ...				J Med Chem 57: 5129-40 (2014) Article DOI: 10.1021/jm401986p BindingDB Entry DOI: 10.7270/Q2833TKT
					More data for this Ligand-Target Pair