BDBM50022498 6-Chloro-3,4-dihydro-2H-benzo[h]chromene-4-carboxylic acid::CHEMBL82424

SMILES: OC(=O)C1CCOc2c1cc(Cl)c1ccccc21

InChI Key: InChIKey=QRWJRWJPCOESHY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50022498 (6-Chloro-3,4-dihydro-2H-benzo[h]chromene-4-carboxy...) Show SMILES OC(=O)C1CCOc2c1cc(Cl)c1ccccc21 Show InChI InChI=1S/C14H11ClO3/c15-12-7-11-10(14(16)17)5-6-18-13(11)9-4-2-1-3-8(9)12/h1-4,7,10H,5-6H2,(H,16,17)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of partially purified calf lens aldose reductase				J Med Chem 31: 230-43 (1988) BindingDB Entry DOI: 10.7270/Q27D2VQF
					More data for this Ligand-Target Pair