BDBM50022763 CHEMBL3298462

SMILES: Fc1cccc(OCc2ccc3C(=O)N(CC4CC4)CCc3n2)c1

InChI Key: InChIKey=ISDJKQUVXHKWIC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50022763 (CHEMBL3298462) Show SMILES Fc1cccc(OCc2ccc3C(=O)N(CC4CC4)CCc3n2)c1 Show InChI InChI=1S/C19H19FN2O2/c20-14-2-1-3-16(10-14)24-12-15-6-7-17-18(21-15)8-9-22(19(17)23)11-13-4-5-13/h1-3,6-7,10,13H,4-5,8-9,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...				J Med Chem 57: 5620-37 (2014) Article DOI: 10.1021/jm500259z BindingDB Entry DOI: 10.7270/Q2736SHB
					More data for this Ligand-Target Pair