BDBM50022792 4-Chloro-1-oxo-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoline-7-carboxylic acid::CHEMBL122500

SMILES: OC(=O)c1ccc2C(Cl)CC3CC(=O)N3c2c1

InChI Key: InChIKey=NILNONPRPJNISS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (TEM-1) (Escherichia coli)	BDBM50022792 (4-Chloro-1-oxo-2,2a,3,4-tetrahydro-1H-azeto[1,2-a]...) Show SMILES OC(=O)c1ccc2C(Cl)CC3CC(=O)N3c2c1 Show InChI InChI=1S/C12H10ClNO3/c13-9-4-7-5-11(15)14(7)10-3-6(12(16)17)1-2-8(9)10/h1-3,7,9H,4-5H2,(H,16,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-CERCOA Curated by ChEMBL					Assay Description Inhibition constant (Ki) for TEM-1 beta-lactamase				J Med Chem 31: 370-4 (1988) BindingDB Entry DOI: 10.7270/Q21R6PHS
					More data for this Ligand-Target Pair