BDBM50022838 Ac-Pro-Phe-His-Sta-NH2::CHEMBL316614

SMILES: CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C=O)C(O)CC(N)=O

InChI Key: InChIKey=SCXHBTGREGDHHQ-VDYHLHOTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022838 (Ac-Pro-Phe-His-Sta-NH2 | CHEMBL316614) Show SMILES CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C=O)C(O)CC(N)=O Show InChI InChI=1S/C29H41N7O6/c1-18(2)11-21(25(38)14-26(30)39)33-28(41)23(13-20-15-31-16-32-20)34-27(40)22(12-19-7-4-3-5-8-19)35-29(42)24-9-6-10-36(24)17-37/h3-5,7-8,15-18,21-25,38H,6,9-14H2,1-2H3,(H2,30,39)(H,31,32)(H,33,41)(H,34,40)(H,35,42)/t21?,22-,23-,24-,25?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against human plasma renin				J Med Chem 31: 18-30 (1988) BindingDB Entry DOI: 10.7270/Q2C53MDQ
					More data for this Ligand-Target Pair