BDBM50022839 Ac-Ftr-Pro-Phe-His-Phe-Phe-NH2::CHEMBL217629

SMILES: CC(=O)N[C@@H](Cc1cn(C=O)c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=ZPHZCFVFBFIFBT-FUJLPNNASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022839 (Ac-Ftr-Pro-Phe-His-Phe-Phe-NH2 | CHEMBL217629) Show SMILES CC(=O)N[C@@H](Cc1cn(C=O)c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C52H56N10O8/c1-33(64)56-44(27-37-30-61(32-63)45-21-12-11-20-39(37)45)52(70)62-23-13-22-46(62)51(69)60-42(26-36-18-9-4-10-19-36)49(67)59-43(28-38-29-54-31-55-38)50(68)58-41(25-35-16-7-3-8-17-35)48(66)57-40(47(53)65)24-34-14-5-2-6-15-34/h2-12,14-21,29-32,40-44,46H,13,22-28H2,1H3,(H2,53,65)(H,54,55)(H,56,64)(H,57,66)(H,58,68)(H,59,67)(H,60,69)/t40-,41-,42-,43-,44-,46-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against human plasma renin				J Med Chem 31: 18-30 (1988) BindingDB Entry DOI: 10.7270/Q2C53MDQ
					More data for this Ligand-Target Pair