BDBM50022850 CHEMBL102728::Pro-Phe-His-Sta-Leu-Phe-NH2

SMILES: CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=UIIPQHGTWPWAEA-BERNIFFBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022850 (CHEMBL102728 | Pro-Phe-His-Sta-Leu-Phe-NH2) Show SMILES CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C43H61N9O7/c1-26(2)18-32(37(53)23-38(54)48-34(19-27(3)4)41(57)50-33(39(44)55)20-28-12-7-5-8-13-28)49-43(59)36(22-30-24-45-25-47-30)52-42(58)35(21-29-14-9-6-10-15-29)51-40(56)31-16-11-17-46-31/h5-10,12-15,24-27,31-37,46,53H,11,16-23H2,1-4H3,(H2,44,55)(H,45,47)(H,48,54)(H,49,59)(H,50,57)(H,51,56)(H,52,58)/t31-,32?,33-,34-,35-,36-,37?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Company Curated by ChEMBL					Assay Description In vitro inhibitory activity towards porcine kidney renin				J Med Chem 31: 18-30 (1988) BindingDB Entry DOI: 10.7270/Q2C53MDQ
					More data for this Ligand-Target Pair