BDBM50022852 Ac-Ftr-Gly-Phe-His-Phe-Phe-Val-Ftr-NH2::CHEMBL437516

SMILES: CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](Cc1cn(C=O)c2ccccc12)NC(C)=O)C(=O)N[C@@H](Cc1cn(C=O)c2ccccc12)C(N)=O

InChI Key: InChIKey=FMQAJDXQPHSPMN-ZXQBWHKPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022852 (Ac-Ftr-Gly-Phe-His-Phe-Phe-Val-Ftr-NH2 | CHEMBL437...) Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](Cc1cn(C=O)c2ccccc12)NC(C)=O)C(=O)N[C@@H](Cc1cn(C=O)c2ccccc12)C(N)=O Show InChI InChI=1S/C66H71N13O11/c1-40(2)59(66(90)73-50(60(67)84)30-45-35-78(38-80)56-25-15-13-23-48(45)56)77-65(89)53(29-44-21-11-6-12-22-44)75-63(87)52(28-43-19-9-5-10-20-43)74-64(88)55(32-47-33-68-37-70-47)76-62(86)51(27-42-17-7-4-8-18-42)72-58(83)34-69-61(85)54(71-41(3)82)31-46-36-79(39-81)57-26-16-14-24-49(46)57/h4-26,33,35-40,50-55,59H,27-32,34H2,1-3H3,(H2,67,84)(H,68,70)(H,69,85)(H,71,82)(H,72,83)(H,73,90)(H,74,88)(H,75,87)(H,76,86)(H,77,89)/t50-,51-,52-,53-,54-,55-,59-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against human plasma renin				J Med Chem 31: 18-30 (1988) BindingDB Entry DOI: 10.7270/Q2C53MDQ
					More data for this Ligand-Target Pair