BDBM50022865 Boc-Phe-His-Leu-Val-Ile-His-OMe::CHEMBL321937

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC

InChI Key: InChIKey=DACRXUMALCQYAS-JHNSYDJNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50022865 (Boc-Phe-His-Leu-Val-Ile-His-OMe | CHEMBL321937) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC Show InChI InChI=1S/C44H66N10O9/c1-11-27(6)36(41(59)51-34(42(60)62-10)20-30-22-46-24-48-30)54-40(58)35(26(4)5)53-39(57)31(17-25(2)3)49-38(56)33(19-29-21-45-23-47-29)50-37(55)32(18-28-15-13-12-14-16-28)52-43(61)63-44(7,8)9/h12-16,21-27,31-36H,11,17-20H2,1-10H3,(H,45,47)(H,46,48)(H,49,56)(H,50,55)(H,51,59)(H,52,61)(H,53,57)(H,54,58)/t27-,31-,32-,33-,34-,35-,36-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human renin				J Med Chem 31: 284-95 (1988) BindingDB Entry DOI: 10.7270/Q2S75FBX
					More data for this Ligand-Target Pair
Pepsin A (Porcine)	BDBM50022865 (Boc-Phe-His-Leu-Val-Ile-His-OMe | CHEMBL321937) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC Show InChI InChI=1S/C44H66N10O9/c1-11-27(6)36(41(59)51-34(42(60)62-10)20-30-22-46-24-48-30)54-40(58)35(26(4)5)53-39(57)31(17-25(2)3)49-38(56)33(19-29-21-45-23-47-29)50-37(55)32(18-28-15-13-12-14-16-28)52-43(61)63-44(7,8)9/h12-16,21-27,31-36H,11,17-20H2,1-10H3,(H,45,47)(H,46,48)(H,49,56)(H,50,55)(H,51,59)(H,52,61)(H,53,57)(H,54,58)/t27-,31-,32-,33-,34-,35-,36-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against porcine pepsin				J Med Chem 31: 284-95 (1988) BindingDB Entry DOI: 10.7270/Q2S75FBX
					More data for this Ligand-Target Pair
Renin (Mus musculus)	BDBM50022865 (Boc-Phe-His-Leu-Val-Ile-His-OMe | CHEMBL321937) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC Show InChI InChI=1S/C44H66N10O9/c1-11-27(6)36(41(59)51-34(42(60)62-10)20-30-22-46-24-48-30)54-40(58)35(26(4)5)53-39(57)31(17-25(2)3)49-38(56)33(19-29-21-45-23-47-29)50-37(55)32(18-28-15-13-12-14-16-28)52-43(61)63-44(7,8)9/h12-16,21-27,31-36H,11,17-20H2,1-10H3,(H,45,47)(H,46,48)(H,49,56)(H,50,55)(H,51,59)(H,52,61)(H,53,57)(H,54,58)/t27-,31-,32-,33-,34-,35-,36-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against mouse renin				J Med Chem 31: 284-95 (1988) BindingDB Entry DOI: 10.7270/Q2S75FBX
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50022865 (Boc-Phe-His-Leu-Val-Ile-His-OMe | CHEMBL321937) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC Show InChI InChI=1S/C44H66N10O9/c1-11-27(6)36(41(59)51-34(42(60)62-10)20-30-22-46-24-48-30)54-40(58)35(26(4)5)53-39(57)31(17-25(2)3)49-38(56)33(19-29-21-45-23-47-29)50-37(55)32(18-28-15-13-12-14-16-28)52-43(61)63-44(7,8)9/h12-16,21-27,31-36H,11,17-20H2,1-10H3,(H,45,47)(H,46,48)(H,49,56)(H,50,55)(H,51,59)(H,52,61)(H,53,57)(H,54,58)/t27-,31-,32-,33-,34-,35-,36-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against bovine cathepsin D				J Med Chem 31: 284-95 (1988) BindingDB Entry DOI: 10.7270/Q2S75FBX
					More data for this Ligand-Target Pair