BDBM50023157 CHEMBL3298955

SMILES: Oc1cccc(Sc2ccc(s2)C(=O)c2cccc(O)c2)c1

InChI Key: InChIKey=QOCIKMMKHWLHLG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50023157 (CHEMBL3298955) Show SMILES Oc1cccc(Sc2ccc(s2)C(=O)c2cccc(O)c2)c1 Show InChI InChI=1S/C17H12O3S2/c18-12-4-1-3-11(9-12)17(20)15-7-8-16(22-15)21-14-6-2-5-13(19)10-14/h1-10,18-19H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50023157 (CHEMBL3298955) Show SMILES Oc1cccc(Sc2ccc(s2)C(=O)c2cccc(O)c2)c1 Show InChI InChI=1S/C17H12O3S2/c18-12-4-1-3-11(9-12)17(20)15-7-8-16(22-15)21-14-6-2-5-13(19)10-14/h1-10,18-19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis				Eur J Med Chem 82: 394-406 (2014) Article DOI: 10.1016/j.ejmech.2014.05.074 BindingDB Entry DOI: 10.7270/Q2KD20G2
					More data for this Ligand-Target Pair