BDBM50023241 CHEMBL3329732

SMILES: CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2nsnc2c1

InChI Key: InChIKey=UQBANPAGHKSGTE-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023241 (CHEMBL3329732) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2nsnc2c1 Show InChI InChI=1S/C21H24N4O3S2/c1-2-24(15-16-6-4-3-5-7-16)21(26)17-10-12-25(13-11-17)30(27,28)18-8-9-19-20(14-18)23-29-22-19/h3-9,14,17H,2,10-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023241 (CHEMBL3329732) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2nsnc2c1 Show InChI InChI=1S/C21H24N4O3S2/c1-2-24(15-16-6-4-3-5-7-16)21(26)17-10-12-25(13-11-17)30(27,28)18-8-9-19-20(14-18)23-29-22-19/h3-9,14,17H,2,10-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair