BDBM50023268 CHEMBL3329764

SMILES: CC(C)(C)CN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1

InChI Key: InChIKey=UQHUYABXHVOXQO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023268 (CHEMBL3329764) Show SMILES CC(C)(C)CN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C26H31F3N4O3S/c1-25(2,3)17-32(16-19-6-4-5-7-22(19)26(27,28)29)24(34)18-10-12-33(13-11-18)37(35,36)21-8-9-23-20(14-21)15-30-31-23/h4-9,14-15,18H,10-13,16-17H2,1-3H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023268 (CHEMBL3329764) Show SMILES CC(C)(C)CN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C26H31F3N4O3S/c1-25(2,3)17-32(16-19-6-4-5-7-22(19)26(27,28)29)24(34)18-10-12-33(13-11-18)37(35,36)21-8-9-23-20(14-21)15-30-31-23/h4-9,14-15,18H,10-13,16-17H2,1-3H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair