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SMILES: CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)S(=O)(=O)NCCCCc1cccnc1

InChI Key: InChIKey=CUWDEWBTCUPBBR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023318   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50023318
PNG
(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)S(=O)(=O)NCCCCc1cccnc1
Show InChI InChI=1S/C24H26N4O3S/c1-17(2)19-8-10-22-21(14-19)24(29)28-16-20(9-11-23(28)27-22)32(30,31)26-13-4-3-6-18-7-5-12-25-15-18/h5,7-12,14-17,26H,3-4,6,13H2,1-2H3
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PC sid
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PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

Curated by ChEMBL


Assay Description
Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand

J Med Chem 31: 466-72 (1988)


BindingDB Entry DOI: 10.7270/Q2KK99S6
More data for this
Ligand-Target Pair