BDBM50023533 CHEMBL10228::Diphenyl-methanone-4,4'-di-(Carbonic acid mono-tert-butyl ester)

SMILES: CC(C)(C)OC(=O)Oc1ccc(cc1)C(=O)c1ccc(OC(=O)OC(C)(C)C)cc1

InChI Key: InChIKey=YLHGKOYDEQPDAY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50023533 (CHEMBL10228 | Diphenyl-methanone-4,4'-di-(Carbonic...) Show SMILES CC(C)(C)OC(=O)Oc1ccc(cc1)C(=O)c1ccc(OC(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C23H26O7/c1-22(2,3)29-20(25)27-17-11-7-15(8-12-17)19(24)16-9-13-18(14-10-16)28-21(26)30-23(4,5)6/h7-14H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte elastase at 10e-7 M				J Med Chem 31: 1052-61 (1988) BindingDB Entry DOI: 10.7270/Q2PC31DJ
					More data for this Ligand-Target Pair