null
SMILES: CC(C)C[C@H](NC(=O)Cn1cc(C(=O)C(F)(F)F)c2cc(NS(=O)(=O)c3ccc(C)cc3)ccc12)C(O)=O
InChI Key: InChIKey=SOOLLEBJNGCDOZ-FQEVSTJZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurotensin receptor type 2 (Rattus norvegicus) | BDBM50023628 (CHEMBL3326831) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 202 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Displacement of [125I]neurotensin from rat NTS2 receptor expressed in CHO-K1 cells by competitive binding assay | J Med Chem 57: 7472-7 (2014) Article DOI: 10.1021/jm500857r BindingDB Entry DOI: 10.7270/Q2BP04C6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (Rattus norvegicus) | BDBM50023628 (CHEMBL3326831) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Displacement of [125I]neurotensin from rat NTS1 receptor expressed in CHO-K1 cells by competitive binding assay | J Med Chem 57: 7472-7 (2014) Article DOI: 10.1021/jm500857r BindingDB Entry DOI: 10.7270/Q2BP04C6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Rattus norvegicus) | BDBM50023628 (CHEMBL3326831) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Antagonist activity at rat NTS2 receptor expressed in CHO-K1 cells assessed as inhibition of SR142948a-induced calcium mobilization by FLIPR assay | J Med Chem 57: 7472-7 (2014) Article DOI: 10.1021/jm500857r BindingDB Entry DOI: 10.7270/Q2BP04C6 | |||||||||||
More data for this Ligand-Target Pair |