BDBM50023749 4-(1,2-diphenyl-vinyl)-phenol::4-[1-(4-hydroxyphenyl)-2-phenylvinyl]phenol::CHEMBL415864

SMILES: [#8]-c1ccc(cc1)-[#6](=[#6]\c1ccccc1)\c1ccc(-[#8])cc1

InChI Key: InChIKey=CKNFKDYCAQZYBQ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (RAT-Rattus norvegicus)	BDBM50023749 (4-(1,2-diphenyl-vinyl)-phenol | 4-[1-(4-hydroxyphe...) Show SMILES [#8]-c1ccc(cc1)-[#6](=[#6]\c1ccccc1)\c1ccc(-[#8])cc1 Show InChI InChI=1S/C20H16O2/c21-18-10-6-16(7-11-18)20(14-15-4-2-1-3-5-15)17-8-12-19(22)13-9-17/h1-14,21-22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystol				J Med Chem 31: 1471-5 (1988) BindingDB Entry DOI: 10.7270/Q2DN478W
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM50023749 (4-(1,2-diphenyl-vinyl)-phenol | 4-[1-(4-hydroxyphe...) Show SMILES [#8]-c1ccc(cc1)-[#6](=[#6]\c1ccccc1)\c1ccc(-[#8])cc1 Show InChI InChI=1S/C20H16O2/c21-18-10-6-16(7-11-18)20(14-15-4-2-1-3-5-15)17-8-12-19(22)13-9-17/h1-14,21-22H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%				J Med Chem 45: 5358-64 (2002) BindingDB Entry DOI: 10.7270/Q2ZK5G19
					More data for this Ligand-Target Pair				3D Structure (crystal)