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BDBM50023798 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2,N'-dimethoxy-benzamidine::CHEMBL41192

SMILES: CCN(CC)CCNC(=NOC)c1cc(Cl)c(N)cc1OC

InChI Key: InChIKey=UEOPSCRGHLYAHM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023798   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50023798
PNG
(4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2,N'-dim...)
Show SMILES CCN(CC)CCNC(=NOC)c1cc(Cl)c(N)cc1OC |w:9.9|
Show InChI InChI=1S/C15H25ClN4O2/c1-5-20(6-2)8-7-18-15(19-22-4)11-9-12(16)13(17)10-14(11)21-3/h9-10H,5-8,17H2,1-4H3,(H,18,19)
PDB

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PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bristol-Myers Company

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding

J Med Chem 31: 1548-58 (1988)


BindingDB Entry DOI: 10.7270/Q25B032R
More data for this
Ligand-Target Pair