BindingDB logo
myBDB logout

BDBM50023808 4-Amino-2-but-3-enyloxy-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL39556

SMILES: CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC=C

InChI Key: InChIKey=JZXNJMALFOJSIJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023808   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50023808
PNG
(4-Amino-2-but-3-enyloxy-5-chloro-N-(2-diethylamino...)
Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC=C
Show InChI InChI=1S/C17H26ClN3O2/c1-4-7-10-23-16-12-15(19)14(18)11-13(16)17(22)20-8-9-21(5-2)6-3/h4,11-12H,1,5-10,19H2,2-3H3,(H,20,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bristol-Myers Company

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding

J Med Chem 31: 1548-58 (1988)


BindingDB Entry DOI: 10.7270/Q25B032R
More data for this
Ligand-Target Pair