BDBM50023828 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-cyclohexyloxy)-benzamide::CHEMBL433052

SMILES: CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCCC1=O

InChI Key: InChIKey=QIIYAJZQOKYUDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50023828 (4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCCC1=O Show InChI InChI=1S/C19H28ClN3O3/c1-3-23(4-2)10-9-22-19(25)13-11-14(20)15(21)12-18(13)26-17-8-6-5-7-16(17)24/h11-12,17H,3-10,21H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Company Curated by ChEMBL					Assay Description In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding				J Med Chem 31: 1548-58 (1988) BindingDB Entry DOI: 10.7270/Q25B032R
					More data for this Ligand-Target Pair