BDBM50023832 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(pyridin-2-ylmethoxy)-benzamide::CHEMBL417148

SMILES: CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCc1ccccn1

InChI Key: InChIKey=WJXMHSPYDSGKRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50023832 (4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(pyrid...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCc1ccccn1 Show InChI InChI=1S/C19H25ClN4O2/c1-3-24(4-2)10-9-23-19(25)15-11-16(20)17(21)12-18(15)26-13-14-7-5-6-8-22-14/h5-8,11-12H,3-4,9-10,13,21H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Company Curated by ChEMBL					Assay Description In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding				J Med Chem 31: 1548-58 (1988) BindingDB Entry DOI: 10.7270/Q25B032R
					More data for this Ligand-Target Pair