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BDBM50023840 3-Amino-2-chloro-11-ethyl-6,7,10,11,12,13,14,15-octahydro-9H-5,8-dioxa-11,15-diaza-benzocyclotetradecen-16-one::CHEMBL41530

SMILES: CCN1CCCNC(=O)c2cc(Cl)c(N)cc2OCCOCC1

InChI Key: InChIKey=XVYMPLWZBYVRPM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023840   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50023840
PNG
(3-Amino-2-chloro-11-ethyl-6,7,10,11,12,13,14,15-oc...)
Show SMILES CCN1CCCNC(=O)c2cc(Cl)c(N)cc2OCCOCC1
Show InChI InChI=1S/C16H24ClN3O3/c1-2-20-5-3-4-19-16(21)12-10-13(17)14(18)11-15(12)23-9-8-22-7-6-20/h10-11H,2-9,18H2,1H3,(H,19,21)
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PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bristol-Myers Company

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding

J Med Chem 31: 1548-58 (1988)


BindingDB Entry DOI: 10.7270/Q25B032R
More data for this
Ligand-Target Pair