BDBM50023846 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-methyl-2-oxo-butoxy)-benzamide::CHEMBL39173

SMILES: CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(=O)CC

InChI Key: InChIKey=SCZOBUCEGRITKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50023846 (4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-met...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(=O)CC Show InChI InChI=1S/C18H28ClN3O3/c1-5-16(23)12(4)25-17-11-15(20)14(19)10-13(17)18(24)21-8-9-22(6-2)7-3/h10-12H,5-9,20H2,1-4H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Company Curated by ChEMBL					Assay Description In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding				J Med Chem 31: 1548-58 (1988) BindingDB Entry DOI: 10.7270/Q25B032R
					More data for this Ligand-Target Pair