BDBM50023847 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-ethyl-2-oxo-propoxy)-benzamide::CHEMBL39930

SMILES: CCC(Oc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC)C(C)=O

InChI Key: InChIKey=STINTIGQRLYQGY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50023847 (4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-eth...) Show SMILES CCC(Oc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC)C(C)=O Show InChI InChI=1S/C18H28ClN3O3/c1-5-16(12(4)23)25-17-11-15(20)14(19)10-13(17)18(24)21-8-9-22(6-2)7-3/h10-11,16H,5-9,20H2,1-4H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Company Curated by ChEMBL					Assay Description In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding				J Med Chem 31: 1548-58 (1988) BindingDB Entry DOI: 10.7270/Q25B032R
					More data for this Ligand-Target Pair