BDBM50024138 CHEMBL3325533

SMILES: Fc1cc(c(F)cc1OC[C@@H]1CNC[C@H]1c1ccc(Cl)cc1)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=SIRNXKYIEVRLCF-JSGCOSHPSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50024138 (CHEMBL3325533) Show SMILES Fc1cc(c(F)cc1OC[C@@H]1CNC[C@H]1c1ccc(Cl)cc1)S(=O)(=O)Nc1ncns1 |r| Show InChI InChI=1S/C19H17ClF2N4O3S2/c20-13-3-1-11(2-4-13)14-8-23-7-12(14)9-29-17-5-16(22)18(6-15(17)21)31(27,28)26-19-24-10-25-30-19/h1-6,10,12,14,23H,7-9H2,(H,24,25,26)/t12-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...				Bioorg Med Chem Lett 24: 4397-401 (2014) Article DOI: 10.1016/j.bmcl.2014.08.017 BindingDB Entry DOI: 10.7270/Q2FF3TX9
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