BDBM50024201 (+/-)2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine::2-(2,3-Dimethoxy-phenyl)-1-methyl-ethylamine::2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine::2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine(3,4-DMA)::CHEMBL277540
SMILES: COc1ccc(CC(C)N)cc1OC
InChI Key: InChIKey=KAZPHAGSWZTKDW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50024201 ((+/-)2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand | J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...) | BDBM50024201 ((+/-)2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine ...) | PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand. | J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50024201 ((+/-)2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension | J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT) | BDBM50024201 ((+/-)2-(3,4-Dimethoxy-phenyl)-1-methyl-ethylamine ...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.55E+3 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundus | J Med Chem 24: 1414-21 (1982) BindingDB Entry DOI: 10.7270/Q2SX6FD3 | |||||||||||
More data for this Ligand-Target Pair |