BDBM50024209 (+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine::(-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine::(R)-(-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine::(S)-(+)2-(4-Methoxy-phenyl)-1-methyl-ethylamine::2-(4-Methoxy-phenyl)-1-methyl-ethylamine::2-(4-Methoxy-phenyl)-1-methyl-ethylamine(PMA)::CHEMBL278663::beta-methoxyamphetamine::para-Methoxyamphetamine

SMILES: COc1ccc(CC(C)N)cc1

InChI Key: InChIKey=NEGYEDYHPHMHGK-UHFFFAOYSA-N

Data: 3 KI  2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50024209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Chile Curated by ChEMBL					Assay Description Inhibition of MAOA in rat brain mitochondria				Bioorg Med Chem 17: 2452-60 (2009) Article DOI: 10.1016/j.bmc.2009.01.074 BindingDB Entry DOI: 10.7270/Q2KW5GZ3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	3.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand				J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.				J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT reuptake at rat SERT expressed in HEK293 cells after 2 mins by liquid scintillation counting				Eur J Med Chem 44: 4862-88 (2009) Article DOI: 10.1016/j.ejmech.2009.07.027 BindingDB Entry DOI: 10.7270/Q24J0F7W
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT)	BDBM50024209 ((+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine | (-...) Show SMILES COc1ccc(CC(C)N)cc1 Show InChI InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundus				J Med Chem 24: 1414-21 (1982) BindingDB Entry DOI: 10.7270/Q2SX6FD3
					More data for this Ligand-Target Pair