null

SMILES: Fc1cc(c(F)cc1OC[C@@H]1CNCC[C@H]1c1ccccc1)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=WNPQUCQKSFDNDS-GJZGRUSLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50024243 (CHEMBL3325522) Show SMILES Fc1cc(c(F)cc1OC[C@@H]1CNCC[C@H]1c1ccccc1)S(=O)(=O)Nc1ncns1 |r| Show InChI InChI=1S/C20H20F2N4O3S2/c21-16-9-19(31(27,28)26-20-24-12-25-30-20)17(22)8-18(16)29-11-14-10-23-7-6-15(14)13-4-2-1-3-5-13/h1-5,8-9,12,14-15,23H,6-7,10-11H2,(H,24,25,26)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...				Bioorg Med Chem Lett 24: 4397-401 (2014) Article DOI: 10.1016/j.bmcl.2014.08.017 BindingDB Entry DOI: 10.7270/Q2FF3TX9
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50024243 (CHEMBL3325522) Show SMILES Fc1cc(c(F)cc1OC[C@@H]1CNCC[C@H]1c1ccccc1)S(=O)(=O)Nc1ncns1 |r| Show InChI InChI=1S/C20H20F2N4O3S2/c21-16-9-19(31(27,28)26-20-24-12-25-30-20)17(22)8-18(16)29-11-14-10-23-7-6-15(14)13-4-2-1-3-5-13/h1-5,8-9,12,14-15,23H,6-7,10-11H2,(H,24,25,26)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...				Bioorg Med Chem Lett 24: 4397-401 (2014) Article DOI: 10.1016/j.bmcl.2014.08.017 BindingDB Entry DOI: 10.7270/Q2FF3TX9
					More data for this Ligand-Target Pair