null

SMILES: COc1ccc(cc1OC)-c1cnc2[nH]cc(NC(=O)C3CCCCC3)c2c1

InChI Key: InChIKey=QVADIDYLQUXJQI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50024286 (CHEMBL3334981) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(NC(=O)C3CCCCC3)c2c1 Show InChI InChI=1S/C22H25N3O3/c1-27-19-9-8-15(11-20(19)28-2)16-10-17-18(13-24-21(17)23-12-16)25-22(26)14-6-4-3-5-7-14/h8-14H,3-7H2,1-2H3,(H,23,24)(H,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...				J Med Chem 62: 5810-5831 (2019) Article DOI: 10.1021/acs.jmedchem.9b00136
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17B (Homo sapiens (Human))	BDBM50024286 (CHEMBL3334981) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(NC(=O)C3CCCCC3)c2c1 Show InChI InChI=1S/C22H25N3O3/c1-27-19-9-8-15(11-20(19)28-2)16-10-17-18(13-24-21(17)23-12-16)25-22(26)14-6-4-3-5-7-14/h8-14H,3-7H2,1-2H3,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Binding affinity to DRAK2 (unknown origin) ATP site				J Med Chem 57: 7624-43 (2014) Article DOI: 10.1021/jm5007929 BindingDB Entry DOI: 10.7270/Q25X2BH3
					More data for this Ligand-Target Pair