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SMILES: O\C(=C/C(=O)c1cc[nH]c1)c1ccc(Cc2ccc(F)cc2)o1

InChI Key: InChIKey=MKQNZEDJGQTSFS-YVLHZVERSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024289   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50024289
PNG
(CHEMBL425146)
Show SMILES O\C(=C/C(=O)c1cc[nH]c1)c1ccc(Cc2ccc(F)cc2)o1
Show InChI InChI=1S/C18H14FNO3/c19-14-3-1-12(2-4-14)9-15-5-6-18(23-15)17(22)10-16(21)13-7-8-20-11-13/h1-8,10-11,20,22H,9H2/b17-10-
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a<1.00E+3n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Concentration required to inhibit catalytic activity of human immuno deficiency virus type 1 integrase

J Med Chem 48: 111-20 (2005)


Article DOI: 10.1021/jm0496077
BindingDB Entry DOI: 10.7270/Q28S4PD6
More data for this
Ligand-Target Pair