BDBM50024434 (+/-) 2-Tetradecyl-oxirane-2-carboxylic acid-Coenzyme A::CHEMBL275981
SMILES: CCCCCCCCCCCCCCC1(CO1)C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12
InChI Key: InChIKey=FMDHVJHZLDKFHK-IOXQRTBXSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carnitine palmitoyltransferase 1A (Rattus norvegicus) | BDBM50024434 ((+/-) 2-Tetradecyl-oxirane-2-carboxylic acid-Coenz...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of carnitine palmitoyl transferase (CPT), assessed with isolated rat liver mitochondria | J Med Chem 30: 1094-7 (1987) BindingDB Entry DOI: 10.7270/Q20P0Z1J | |||||||||||
More data for this Ligand-Target Pair |