BDBM50024447 (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::CHEMBL17695::HETE-(+/-)5::HETE-5(S)

SMILES: CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O

InChI Key: InChIKey=KGIJOOYOSFUGPC-XTDASVJISA-N

Data: 4 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50024447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP Ki Database									J Biol Chem 275: 40686-94 (2000) Article DOI: 10.1074/jbc.M004512200 BindingDB Entry DOI: 10.7270/Q2XD1066
					More data for this Ligand-Target Pair
Leukotriene 2 (Homo sapiens (Human))	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP Ki Database									J Biol Chem 275: 40686-94 (2000) Article DOI: 10.1074/jbc.M004512200 BindingDB Entry DOI: 10.7270/Q2XD1066
					More data for this Ligand-Target Pair
Leukotriene 2 (Homo sapiens (Human))	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP Ki Database									J Biol Chem 275: 40686-94 (2000) Article DOI: 10.1074/jbc.M004512200 BindingDB Entry DOI: 10.7270/Q2XD1066
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by PDSP Ki Database									J Biol Chem 275: 40686-94 (2000) Article DOI: 10.1074/jbc.M004512200 BindingDB Entry DOI: 10.7270/Q2XD1066
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50024447 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase				J Med Chem 30: 254-63 (1987) BindingDB Entry DOI: 10.7270/Q2028S4N
					More data for this Ligand-Target Pair